SCILLS - The Scottish Institute for Cell Signalling

SCILLS is dedicated to the study of how biological processes are controlled and how they become deregulated in disease. The Protein Ubiquitination Unit is the Institute’s first research Division. Its major aims are to advance understanding of the role of protein ubiquitination and related modifications in cell regulation and human disease, to facilitate the development of drugs to treat diseases caused by abnormalities in this process, to generate reagents and improve technologies on which more rapid progress in this area depends, and to train the next generation of scientists who will advance the subject.

Protein Production and Assay Development

The Protein Production and Assay Development Team produce the E2 conjugating enzymes, the E3 ubiquitin ligases and the deubiquitinases required by the Unit.